This book I think I could definitely have gone without. I’m quite disappointed. Unfortunately most of the book deals with advanced maternal age/ovarian failure (or at least egg quality declining). Which to me is pretty useless, since I am early-20’s and my eggs have passed every test so far except IVF – even the test that Dr. Silber recommends, which is the antral follicle count. So unfortunately a lot of the book could be really great information but is useless to me.
There were a couple of facts that I bookmarked.
First, within the first paragraph of the book, he states some statistics about infertility rates. It’s all relating back to his whole “older is worse” topic, but at least he mentions my age-group.
The incidence of infertility is rare. For women in their early twenties, only 1 to 2 percent are infertile. In their late twenties, 16 percent are infertile, and in their mid- to late thirties, 25 percent are infertile.
It’s always nice to hear that I’m one of a select 2 percent. I’m special, I guess.
The next thing I bookmarked talked about egg retrieval rate corresponding with pregnancy rates in IVF. For women under 30 if fewer than 10 eggs were retrieved the pregnancy rate was 50%. If 10 or more eggs were retrieved the pregnancy rate jumps to 66%. Of course for older patients the pregnancy rate significantly declines if there are less than 10 eggs – but regardless of age if 10 or more eggs were retrieved the pregnancy rate remains nearly 50%! Even in the “over 40 years old” group.
This was Silber’s entire point of the book – that while maternal age is a pretty good indication of declining fertility, the only way to tell where a specific patient is sitting in terms of their fertility is looking at their antral follicle count (which directly correlates to the number of eggs retrieved). That part of the book was a good read, and something I didn’t know. Every day in a woman’s body a group of eggs starts growing into antral follicles. When they hit a certain size (antral follicle size) then they are in the “pool” to be selected by the next cycle. Normally of course only one egg is selected to be the chosen one; the rest die. But from what Silber says it’s a different group of antral follicles every day… every day 30 (or however many) eggs grow to size and then die. Every single day of your life. and only on that one lucky day at the start of your cycle does one of that day’s group get selected. This is how we lose so many eggs over the course of our lifetime. So next time you get an ultrasound when you’re not stimming or ovulating? That’s what the antral follicle count is – how many eggs are in that “pool”… which indicates how fertile you are. (Small number of eggs is a significant sign of declining fertility and decreased chances for pregnancy, according to Dr. Silber.)
Another part I bookmarked was the section in the IVF chapter entitled Rationale for Doing IVF Sooner in All Cases of Infertility. This is the other of Silber’s main points in his book: he fully advocates skipping all the testing, all the clomid, all the IUIs, and moving straight to IVF. I do think he mentions that in the case where a woman isn’t ovulating it makes sense to first get her to ovulate, but in cases of unexplained? His point is exactly what our reasoning was – it appears everything is working fine, you have an egg released every month, and no one knows what exactly is going wrong along the way. So instead of taking shot after shot in the dark, both wasting money and creating a lot of demoralization in the couple, he suggests going straight to IVF and getting pregnant right off the bat. IVF bypasses almost every problem along the way, so it can solve pretty much every fertility problem. Plus of course he says in the cases where women are older and their fertility is declining rapidly wasting time with testing and lesser methods may mean that by the time the couple get to IVF as an option it’s too late, her eggs are already too few.
Another point he makes in the book was ranting a bit about endometriosis and laparoscopic surgery. He claimed that – at least in previous years – it was “popular” to do laps and give diagnoses of “minimal endometriosis.” His suggestion was that doctors feel better giving some sort of diagnosis, plus that insurance is much more willing to pay for these surgeries if something is actually found. So yes, he suggests that a lot of of the “minimal endo” are basically a crock. Which made me feel pretty crappy. There is a part of me that feels in agreement however, because even when talking to my doctor about my “minimal endo” it was clear there were only a couple of tiny spots. And quite obviously lasering them has had NO effect on my menstrual pain and nausea. Den’s point was that at least we know it’s not worse, which is of course why I did it in the first place – and my doctor was not the one requesting the surgery, it was all me, so I certainly can’t say that she’s one of the doctors who are “pushing” for laparoscopies! She was very clear that if I had minimal endo it probably wouldn’t make a difference to our fertility one way or the other.
Edited:
I’ve been reading more of the book and had to come update my opinions here. It’s true that a lot of the book is not applicable to me… but I’m starting to “feel” it more. He has a whole chapter on emotions and relaxation. Thankfully he does make the point that for any doctor to tell your patient to relax (or anyone tell tell you to relax!) does absolutely nothing but stress the person out more. He says specifically, “Reassurance that is not evidence based only increases a couple’s anxiety.” Which I think we would all agree with. He also talks about how much of the anxiety and stress that infertile couples deal with is directly caused by the infertility – not the other way around.
And I’m glad he starts out the chapter that way, because it put me in a good, open-minded mood. From there he talks about IVF success rates with calm, relaxed patients and stressed out anxious patients. And I’m inclined to listen. I mean I’m never going to be able to not worry at all through this process – but I’ll obviously do everything I can, including trying my utmost best to relax throughout the transfer process. I might even schedule a massage around that time – I’m sure Den would say it would be money well spent. Dr. Silber talks about vibrations/contractions of the uterus of anxious women and how any disturbance is bad. He says his clinic only uses very soft catheters so as not to unintentionally irritate anything.
So I guess I can’t say this book has been completely useless. I’m not 100% sold on it, but it’s an interesting point of view for sure. I do wish I’d read it a couple of months ago though – I might have made a different choice regarding the lap. Oh well, that’s done, and I suffered no ill-effects from it.
One thing it has definitely helped me with is choosing which workshops to go to at the AFA conference. I am not going to go to the endometriosis panel, given my extremely minimal situation. And I am going to go to the panel on relaxation and stress.